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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NPHP3
All Species:
13.94
Human Site:
S467
Identified Species:
34.07
UniProt:
Q7Z494
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7Z494
NP_694972.3
1330
150864
S467
L
E
T
K
D
L
G
S
E
D
S
I
P
E
E
Chimpanzee
Pan troglodytes
XP_516758
2073
234018
S480
L
E
T
K
D
L
G
S
E
D
S
I
P
E
E
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_863943
2040
230770
S447
R
E
T
K
D
L
G
S
E
D
S
I
P
E
E
Cat
Felis silvestris
Mouse
Mus musculus
Q7TNH6
1324
150168
R463
V
E
E
K
D
G
G
R
E
D
S
T
P
E
E
Rat
Rattus norvegicus
XP_343462
1325
150597
S463
V
E
V
K
D
G
G
S
E
D
S
S
P
E
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514031
1275
145541
F437
E
Q
E
Q
I
E
A
F
Q
Q
A
S
N
S
T
Chicken
Gallus gallus
XP_418790
1315
149161
N449
L
E
G
K
D
L
G
N
K
E
E
S
T
A
P
Frog
Xenopus laevis
Q6AZT7
1300
148301
A442
P
D
A
K
D
E
S
A
T
M
E
D
D
D
Y
Zebra Danio
Brachydanio rerio
XP_691073
1303
148244
E451
N
G
V
V
E
E
R
E
E
E
D
S
G
D
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001203493
1012
113472
S203
D
W
W
T
V
L
E
S
E
P
S
L
G
S
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
61.7
N.A.
61.5
N.A.
88.8
87.9
N.A.
78
83.9
76.9
69.9
N.A.
N.A.
N.A.
N.A.
30.9
Protein Similarity:
100
62.4
N.A.
63
N.A.
93.3
93.3
N.A.
86.2
90.7
86.5
82.9
N.A.
N.A.
N.A.
N.A.
49.1
P-Site Identity:
100
100
N.A.
93.3
N.A.
66.6
73.3
N.A.
0
40
13.3
6.6
N.A.
N.A.
N.A.
N.A.
26.6
P-Site Similarity:
100
100
N.A.
93.3
N.A.
73.3
80
N.A.
26.6
60
33.3
26.6
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
0
0
10
10
0
0
10
0
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
10
0
0
70
0
0
0
0
50
10
10
10
20
0
% D
% Glu:
10
60
20
0
10
30
10
10
70
20
20
0
0
50
50
% E
% Phe:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% F
% Gly:
0
10
10
0
0
20
60
0
0
0
0
0
20
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
10
0
0
0
0
0
0
30
0
0
0
% I
% Lys:
0
0
0
70
0
0
0
0
10
0
0
0
0
0
0
% K
% Leu:
30
0
0
0
0
50
0
0
0
0
0
10
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
10
% M
% Asn:
10
0
0
0
0
0
0
10
0
0
0
0
10
0
0
% N
% Pro:
10
0
0
0
0
0
0
0
0
10
0
0
50
0
10
% P
% Gln:
0
10
0
10
0
0
0
0
10
10
0
0
0
0
0
% Q
% Arg:
10
0
0
0
0
0
10
10
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
10
50
0
0
60
40
0
20
0
% S
% Thr:
0
0
30
10
0
0
0
0
10
0
0
10
10
0
10
% T
% Val:
20
0
20
10
10
0
0
0
0
0
0
0
0
0
10
% V
% Trp:
0
10
10
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _